Four dimensions createsixteen current-state combinations.
Each code follows M–I–N–E: metabolism, immunity, nerve and energy. Combinations organize results and conversation; they are not personality types or fixed labels.
Eight basic directions
Understand the directions before reading a combination.
Each dimension has two directions. They describe a current self-report tendency, with an observation focus to help interpret the result.
01M · Metabolism
BBurn
Metabolic mobilization and state initiation tend to be faster.
Observation focusRecovery after sustained high-intensity schedules.
RReserve
Energy-storage tendency is more evident, with a preference for steady release.
Observation focusThe relationship between food, activity and weight changes.
02I · Immunity
TTank
State and recovery appear relatively stable as conditions change.
Observation focusMaintaining a regular routine and stable daily rhythm.
AAlert
More sensitive to changes in environment, routine or diet.
Observation focusRecurring environmental or rhythm-related triggers.
03N · Nerve
CConcentrate
Sustained attention and information organization tend to be stronger.
Observation focusKeeping a balance between focus and timely rest.
JJump
Thoughts shift actively and connect across multiple threads.
Observation focusReducing task switching and returning to the current priority.
04E · Energy
FFlash
Energy initiation and short-term mobilization tend to be faster.
Observation focusSleep and recovery after high-intensity activity.
SSteady
Energy recovery may take longer and suits gradual progression.
Observation focusBuilding activity step by step without repeated overextension.
Combination matrix
Four direction choices form one MINE code.
Read N / E across the top and M / I down the side. Each intersection is one current-state combination.
N / E columns
M / I rowsM / I
CFConcentrate · Flash
CSConcentrate · Steady
JFJump · Flash
JSJump · Steady
BTBurn · Tank
BABurn · Alert
RTReserve · Tank
RAReserve · Alert
BTBurn · Tank
BABurn · Alert
RTReserve · Tank
RAReserve · Alert
Selected combinationBTCF
Current pattern
Metabolic mobilization and state initiation tend to be faster. State and recovery appear relatively stable as conditions change. Sustained attention and information organization tend to be stronger. Energy initiation and short-term mobilization tend to be faster.
Observation focus
Recovery after sustained high-intensity schedules. Maintaining a regular routine and stable daily rhythm. Keeping a balance between focus and timely rest. Sleep and recovery after high-intensity activity.
The combination summary uses this questionnaire's direction scores. When the two sides are close, the result is shown as balanced or provisional and should be read with the scores and assessment scope.
MINE's theoretical foundation
A systems view of aging biologyfor understanding individual differences.
MINE draws on research perspectives on multi-system change, homeostatic regulation and individual heterogeneity in aging biology. It translates complex concepts into everyday experiences that can be described by the individual, creating a structured entry point for self-observation.
M / METABOLISM
Metabolism
Nutrient sensing, glucose and lipid balance; the questionnaire enters through eating, weight change and post-meal experience.
I / IMMUNITY
Immunity
Inflammation regulation, barriers and recovery; the questionnaire enters through discomfort, sensitivity and recovery rhythm.
N / NERVE
Nerve
Neural networks, plasticity and rhythm; the questionnaire enters through attention, information processing and thought switching.
E / ENERGY
Energy
Energy supply, stress response and recovery; the questionnaire enters through energy initiation, sleep recovery and activity tolerance.
Theoretical pillars
Five complementary research perspectives
Life course and initial conditionsEarly development, exposure and lived experience can shape later health trajectories and adaptive responses.
Cell and organelle functionCellular homeostasis, repair, energy use and signaling underpin changes across body systems.
System dynamics and homeostasisThe body regulates itself to maintain balance; prolonged stress and insufficient recovery may add cumulative load.
Evolutionary trade-offsTraits that support short-term survival or mobilization may have long-term costs in different environments.
Cross-dimension interactionMetabolism, immunity, nerve and energy interact; a state change may affect several dimensions.
How to read this foundation
These are the research background and framework behind MINE. The current questionnaire does not directly measure nutrient sensing, inflammatory pathways, neural plasticity, mitochondrial function or other specific biological mechanisms. Results reflect the current self-report pattern and are not a medical assessment.
SELECTED READING
Research behind the framework
These sources inform the framework's research perspective; they do not validate the questionnaire or its scores.
01
Hallmarks of aging: An expanding universe.López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G.Cell. 2023;186(2):243–278.
Aging and aging-related diseases: from molecular mechanisms to interventions and treatments.Guo J et al.Signal Transduction and Targeted Therapy. 2022;7:391.
03
Allostatic Load and Allostatic Overload: Preventive and Clinical Implications.Pfaltz MC, Schnyder U.Psychotherapy and Psychosomatics. 2023;92:279–282.
The two directions within each dimension are scored independently. They are not combined into one overall health score.
Scoring exampleSingle direction
75points / 100
Suppose the eight questions for one direction average 4.0:
Step 14.0 − 1 = 3.0Move a 1–5 answer to a 0–4 scale
↓
Step 23.0 × 25 = 75Convert the 0–4 scale to 0–100
64
questionnaire items16 questions per dimension
8
questions per directioneight independent direction scores
1–5
self-rating scaleEach selected level enters its direction score directly
Difference between two directions
|difference| = 0Balanced
0 < |difference| < 10Provisional tendency
|difference| ≥ 10Clearer tendency
Example: a small gap61 − 55 = 6
If two directions score 61 and 55, the 6-point gap is below 10, so it is shown as a provisional tendency.
How to read the result Scores reflect direction tendencies in this self-report questionnaire. They are not disease risk, biological age or organ-function measurements, and do not replace medical diagnosis.
SELF-OBSERVATION
See how the framework describes your current pattern.
Complete the 64-question assessment to review your four dimensions and eight direction scores.